Genetic study explains rising colorectal cancer in youth
Young adults’ tumors show threefold mutation increase tied to gut bacteria
Genetic study and colorectal cancer
On 10 July 2025, IARC, in collaboration with UC San Diego and the Sanger Institute, published results about cancer in youth. Colorectal tumors in adults under 40 had over three times more mutations than those in people over 70. These mutations correlated with specific gut bacteria, suggesting microbiome‑driven carcinogenesis. The study of more than 1,000 tumor samples points toward new microbial biomarkers. It supports the development of microbiome‑based early screening and prevention strategies.
#EuCanScreen #CancerScreening #HealthCare #CancerPrevention #ColorectalCancer #GeneticMutation #CancerYouth
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The general objective of EUCanScreen is to assure sustainable implementation of high-quality screening for breast, cervical and colorectal cancers, as well as implementation of the recently recommended screening programs – for lung, prostate and gastric cancers. EUCanScreen will facilitate the reduction of cancer burden and achieving equity across the EU.
This project has received funding from the European Union’s EU4HEALTH Programme under the Grant Agreement no 101162959